Computational Molecular Biology - an overview

Genomic research is experiencing a shift of paradigm. Old reductionistic research methods are largely replaced by methods and technology that make possible conducting global studies of gene products and their interactions in complex networks in living organisms. Computational data analysis and modelling have become an important and necessary part of this research methodology. In this paper we look at some of the most commonly used methods for data analysis and modelling, and discuss some of the most important publications taking these methods into use in real-world biological studies.